As a local multiplayer title, Crawl stands out amongst other roguelikes. It's fun and simple gameplay is easy to pick-up for pretty much any level of gamer. However, without friends to play it with, this is not a game worth playing. Alone, Crawl runs at a pace that lives up to its name.
It's also not a very long game. My first playthrough clocked in at around seven hours, though better players could certainly finish it more quickly. There's also nothing new to do once you've slain Vroll. But if you have a thing for the difficult platformers of yore, Slain: Back from Hell is a satisfying blend of what made those games great.
They're a sight to behold and marginally more fun to play than the levels that house them. Sine Mora is a good-looking game and it's clear that a lot of effort was put into making it that way. It's just a shame that it's not as fun to play as it is to watch in motion.
Vaccine isn't a title I'd recommend even to the most fervent survival horror fans. There just isn't enough variation to continue playing death after death. Stay away from this one.