The act of reloading a save to reverse an unwanted outcome, often called save scumming, is a contentious topic in gaming. Some would rather you face the consequences of your actions regardless of the outcome, while others prefer having the ability to keep retrying until they get the exact results they desire.
Fallout: New Vegas, Pentiment and Pillars of Eternity game director Josh Sawyer recently expressed the former opinion on social media saying, "Manual save games were a mistake. They are the chicken nuggies of gaming: they bring you comfort but are bad for you and poison your gaming spirit."
Saving has always been all over the place in gaming. While the practice of having to finish a game in a single session is a thing of the past, there is still a variety of saving methods observable in triple-A games. You have the standard game that allows manual saving alongside regular autosaves, you have games that operate on a checkpoint system and games where you can only save at checkpoints.
Sawyer is presumably advocating for a game that doesn't allow for manual saving and auto-saving after major events, essentially 'locking in' whatever decisions you made to reach that...