Resident Evil HD Remaster is just as good as the original in most ways, and in others better. Resident Evil HD feels great, looks great, and the controls are wonderfully remade for the newer systems. It can get a little hard at times figuring out your way, but that is what makes Resident Evil one of the hardest, yet most accomplished games in the series to have ever been released.
The best way to play this is first, try to take it seriously. Try to act like you are a true surgeon and see how far you get. After that becomes boring, have some fun, try using things like a hammer to break the ribs of poor Bob, using a drill to take his eyes out, and using a laser to cut his brain out. All of these things can be used to make a game so simple, so fun.
In my reviews I like to tell gamers out there my personal favorite way to play games. For Velocity 2X I definitely would turn any sound system up as loud as it can comfortably go and let the game's music take you on a journey just as far as the game itself will take you.