Orin the Red in her Slayer form is one of the most powerful opponents in Baldur's Gate 3, with some suggesting that she's more difficult to defeat than the Netherbrain in Honour Mode. The combination of her Unstoppable stacks and powerful boons and abilities like Power Word: Kill and Bhaal's Edict make navigating this fight a tricky endeavour for all but the most overpowered of parties.
However, a new "cheese" strategy has been discovered courtesy of Reasonable_Run3567 on Reddit. This exploit allows you to kill Orin without ever having to witness her terrifying Slayer form. First, you'll need to one-shot Orin at Rivington while she's disguised as Lens the Journalist with non-lethal attacks toggled. The original poster believes a one-shot is necessary, presumably to prevent dialogue with Orin from triggering. Orin's undisguised form will then appear, and you'll be able to reduce her hit points to 1 without triggering a response.
Later, Orin will appear at the party camp disguised as the orphan Yenna. This will only occur if none of Lae'zel, Halsin, Minthara or Gale are at camp when the player finds out that they have been infiltrated by Orin. This exploit presumably works...